![]() Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses. A division of Fougera Pharmaceuticals Inc. Store at controlled room temperature 15°- 30☌ (59°-86☏). This resistance is lost when the antibiotic is removed. Nystatin Ointment (100,000 USP Nystatin Units per gram) is a yellow ointment available as follows: NDC 42254-284-15 15 gram tube. She was administered nystatin vaginal tablets, 100,000 units twice daily for 14 days. stellatoides) become quite resistant on treatment with Nystatin and simultaneously become cross resistant to amphotericin as well. Dermatologic side effects associated with nystatin topical powder, cream, and ointment have included skin irritation, burning, itching, rash, eczema, and pain on application in less than 0.1 of patients. Generally, resistance to nystatin does not develop during therapy. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. ![]() Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. The structural formula is as follows: Molecular Weight 926.13. Nystatin Ointment USP, for topical use only, contains 100,000 USP Nystatin Units per gram, in an ointment base of light mineral oil and white petrolatum. krusei, Torulopsis glabrata, Tricophyton rubrum, T. Nystatin is a polyene antifungal antibiotic drug obtained from Streptomyces nursei. Manufactured By Perrigo plc Bronx, NY 10457. Store at 20-25☌ (68-77☏) see USP Controlled Room Temperature. Manufactured for: Macleods Pharma USA, Inc. Store at 20° to 25☌ (68° to 77☏) excursions permitted between 15° to 30☌ (59° to 86☏) See USP Controlled Room Temperature. Microbiology Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. Nystatin Cream USP (100,000 USP Nystatin Units per gram) is a yellow cream available as follows: 15 g tube (NDC 45802-059-35) 30 g tube (NDC 45802-059-11) Storage. Nystatin Cream USP is a yellow to light green cream. ![]() Pharmacokinetics Nystatin is not absorbed from intact skin or mucous membrane. ![]()
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